The Great Healthcare Disruption: How AI Is Reshaping Medicine

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Dr. Marschall Runge’s The Great Healthcare Disruption explores how technology, policy shifts, and new business models are redefining U.S. healthcare. Drawing on his experience as former EVP for Medical Affairs at the University of Michigan and CEO of Michigan Medicine, Runge contends the industry has reached a pivotal moment where converging disruptions are transforming how care is delivered.

The book “The Great Healthcare Disruption: Big Tech, Bold Policy, and the Future of American Medicine” systematically analyzes major healthcare disruptors, including retail medicine (Amazon, CVS, Walmart), emerging gene and mRNA therapies, artificial intelligence applications, new obesity drugs, virtual behavioral health platforms, and novel payment models. Rather than viewing these changes with alarm, Runge advocates embracing and directing disruption to address healthcare’s core challenges: high costs, limited access and uneven quality.

Throughout the text, Runge weaves together clinical insights, policy analysis, and personal observations to illuminate both the promise and perils ahead. He argues that successfully navigating this transformation requires:

  • Reimagining primary care delivery through both virtual and retail channels
  • Leveraging AI and automation to extend provider capabilities
  • Making breakthrough therapies more affordable and accessible
  • Building more resilient systems to handle future crises
  • Shifting focus from treating illness to preventing disease
  • Finding sustainable ways to pay for innovation

The book concludes with a call for proactive change, arguing that passively responding to disruption is insufficient. Instead, healthcare leaders must actively shape how new technologies and business models evolve to ensure they advance core missions of expanding access, improving outcomes and controlling costs.

In an accessible and reader-friendly manner, The Great Healthcare Disruption offers a comprehensive roadmap for healthcare’s future while remaining grounded in practical realities. Runge’s balanced perspective — embracing innovation while acknowledging implementation challenges — makes this a valuable guide for healthcare leaders navigating unprecedented change.

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Taylor Graham, marketing grad with an inner nature to be a perpetual researchist, currently all things IT. Personally and professionally, Taylor is one to know with her tenacity and encouraging spirit. When not working you can find her spending time with friends and family.